Radiologic progression in patients with juvenile chronic arthritis treated with methotrexate
- PMID: 9709717
- DOI: 10.1016/s0022-3476(98)70231-8
Radiologic progression in patients with juvenile chronic arthritis treated with methotrexate
Abstract
We investigated the rate of radiologic progression, as measured by carpal length, in 26 children with juvenile chronic arthritis who were treated with methotrexate. After 2 years of treatment, the carpal length was significantly more deteriorated in nonresponders in both the "better" wrist (P = .001) and the "worse" wrist (P = .005). These results show that methotrexate may have a "disease modifying" potential in juvenile chronic arthritis.
Comment in
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Outcomes research in the therapeutic use of methotrexate in children with chronic peripheral arthritis.J Pediatr. 1998 Aug;133(2):179-80. doi: 10.1016/s0022-3476(98)70217-3. J Pediatr. 1998. PMID: 9709702 No abstract available.
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