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. 1998 Aug;133(2):262-5.
doi: 10.1016/s0022-3476(98)70231-8.

Radiologic progression in patients with juvenile chronic arthritis treated with methotrexate

A Ravelli  1 , S Viola, B Ramenghi, G Beluffi, L A Zonta, A Martini
Affiliations

Radiologic progression in patients with juvenile chronic arthritis treated with methotrexate

A Ravelli et al. J Pediatr. 1998 Aug.

Abstract

We investigated the rate of radiologic progression, as measured by carpal length, in 26 children with juvenile chronic arthritis who were treated with methotrexate. After 2 years of treatment, the carpal length was significantly more deteriorated in nonresponders in both the "better" wrist (P = .001) and the "worse" wrist (P = .005). These results show that methotrexate may have a "disease modifying" potential in juvenile chronic arthritis.

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