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. 1976 Aug;35(4):321-6.
doi: 10.1136/ard.35.4.321.

Immunoglobulin and complement deposition in skin of rheumatoid arthritis and systemic lupus erythematosus patients

A L Schroeter, D L Conn, R E Jordon

Immunoglobulin and complement deposition in skin of rheumatoid arthritis and systemic lupus erythematosus patients

A L Schroeter et al. Ann Rheum Dis. 1976 Aug.

Abstract

Rheumatoid arthritis (RA) was differentiated from systemic lupus erythematosus (SLE) by direct immunofluorescent techniques on skin specimens, using monospecific antisera for IgG, IgM, C3, C1q, properdin, and fibrin. Of 30 patients with RA studied, 20 had dermal vessel deposits of immunoglobulins and complement components in unaffected skin without the characteristic dermal-epidermal junctional fluorescence of SLE. Of 24 SLE patients studied, 24 had granular deposits of immunoglobulins and complement components in unaffected skin at the dermal-epidermal junction.

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References

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