Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1976 Aug;35(4):321-6.
doi: 10.1136/ard.35.4.321.

Immunoglobulin and complement deposition in skin of rheumatoid arthritis and systemic lupus erythematosus patients

A L Schroeter, D L Conn, R E Jordon

Immunoglobulin and complement deposition in skin of rheumatoid arthritis and systemic lupus erythematosus patients

A L Schroeter et al. Ann Rheum Dis. 1976 Aug.

Abstract

Rheumatoid arthritis (RA) was differentiated from systemic lupus erythematosus (SLE) by direct immunofluorescent techniques on skin specimens, using monospecific antisera for IgG, IgM, C3, C1q, properdin, and fibrin. Of 30 patients with RA studied, 20 had dermal vessel deposits of immunoglobulins and complement components in unaffected skin without the characteristic dermal-epidermal junctional fluorescence of SLE. Of 24 SLE patients studied, 24 had granular deposits of immunoglobulins and complement components in unaffected skin at the dermal-epidermal junction.

PubMed Disclaimer

References

    1. J Exp Med. 1964 Feb 1;119:195-209 - PubMed
    1. Br J Dermatol. 1975 Mar;92(3):263-71 - PubMed
    1. Bull Rheum Dis. 1958 Dec;9(4):175-6 - PubMed
    1. Ann Rheum Dis. 1957 Mar;16(1):84-103 - PubMed
    1. Ann Intern Med. 1957 May;46(5):831-51 - PubMed

Publication types