Infection of newborn and fetal hamsters induced by inoculation of LuIII parvovirus
- PMID: 971111
- DOI: 10.1007/BF01318027
Infection of newborn and fetal hamsters induced by inoculation of LuIII parvovirus
Abstract
The LuIII parvovirus was adapted to the newborn hamster and produced a systemic infection with massive intestinal hemorrhage. Inoculation of pregnant hamsters lead to transplacental infection of the fetuses and abortion. Most fetal deaths were observed in animals inoculated on days 8 and 10 of gestation. Virus was recovered from dead fetuses, placentas, and viable fetuses. Histological lesions were found in the heart, liver, kidney and CNS of infected fetuses.
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