Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1998 May 11;93(2-3):79-88.
doi: 10.1016/s0379-0738(98)00029-2.

Band shift analysis of three base-pair repeat alleles in the short tandem repeat locus D12S391

C P Phillips  1 , D Syndercombe Court, M V Lareu, J Hasskamp, A Carracedo
Affiliations

Band shift analysis of three base-pair repeat alleles in the short tandem repeat locus D12S391

C P Phillips et al. Forensic Sci Int. .

Abstract

Two hundred and sixty UK Caucasian individuals have been typed for the STR locus D12S391. Measurements of absolute band shift, relative to an allelic ladder, allowed fragments differing by one base pair to be consistently distinguished. The intermediate alleles typed from such fragments comprised approximately 5% of the total alleles observed in this study. The existence of intermediate alleles in the D12S391 locus, not included in the allelic ladder, allowed us to assess the efficacy of band shift analysis in detecting intermediate alleles on two different automated fluorescent detection platforms. The results of sequencing a sample of intermediate alleles are also presented.

PubMed Disclaimer

LinkOut - more resources