Gene conversion: a hitherto overlooked parameter in population genetics
- PMID: 971809
- PMCID: PMC1213556
- DOI: 10.1093/genetics/83.4.861
Gene conversion: a hitherto overlooked parameter in population genetics
Abstract
Gene conversion causes deviations from the 2:2 segregation of allele pairs in meiosis. Thus, gene conversion is a potential cause for changes of allele frequencies in populations. Equations are derived for the effects of conversion in a large random-mating population. The influence of gene conversion on allele frequencies is compared with that of spontaneous mutation and meiotic drive.
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