Tobramycin and cephalothin sodium in treatment of infected patients with acute leukemia
- PMID: 972277
- DOI: 10.1093/infdis/134.supplement_1.s170
Tobramycin and cephalothin sodium in treatment of infected patients with acute leukemia
Abstract
Tobramycin has been shown to be safe and effective when given intravenously in combination antibiotic therapy for infected patients with acute leukemia or other profound pancytopenic states. Tobramycin in combination with one or more antibiotics (usually cephalothin) produced satisfactory clinical results in 21 of 30 episodes of fever. Toxic effects were minimal and were limited to occasional mild thrombophlebitis.
Similar articles
-
Empiric treatment of fever in acute leukaemia with tobramycin-cephalothin, and the escape clause provision of corticosteroids.Scand J Infect Dis. 1980;12(2):139-48. doi: 10.3109/inf.1980.12.issue-2.13. Scand J Infect Dis. 1980. PMID: 7375825
-
Tobramycin-cephalothin treatment in leukaemic and neutropenic patients with severe infection.J Antimicrob Chemother. 1977 Jul;3(4):311-5. doi: 10.1093/jac/3.4.311. J Antimicrob Chemother. 1977. PMID: 893240 No abstract available.
-
Empiric therapy for cancer patients: comparative study of ticarcillin-tobramycin, ticarcillin-cephalothin, and cephalothin-tobramycin.Antimicrob Agents Chemother. 1975 May;7(5):640-5. doi: 10.1128/AAC.7.5.640. Antimicrob Agents Chemother. 1975. PMID: 1096809 Free PMC article. Clinical Trial.
-
Empiric therapy of febrile granulocytopenic patients.Am J Hosp Pharm. 1979 Feb;36(2):178-87. Am J Hosp Pharm. 1979. PMID: 369364 Review.
-
The use of synergistic combinations of antibiotics in patients with haematological diseases.Clin Haematol. 1976 Jun;5(2):361-77. Clin Haematol. 1976. PMID: 780029 Review. No abstract available.
MeSH terms
Substances
LinkOut - more resources
Full Text Sources