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. 1976 Aug:134 Suppl:S170-4.
doi: 10.1093/infdis/134.supplement_1.s170.

Tobramycin and cephalothin sodium in treatment of infected patients with acute leukemia

P C Vincent, F Jennis, R Hilmer, S Fabre

Tobramycin and cephalothin sodium in treatment of infected patients with acute leukemia

P C Vincent et al. J Infect Dis. 1976 Aug.

Abstract

Tobramycin has been shown to be safe and effective when given intravenously in combination antibiotic therapy for infected patients with acute leukemia or other profound pancytopenic states. Tobramycin in combination with one or more antibiotics (usually cephalothin) produced satisfactory clinical results in 21 of 30 episodes of fever. Toxic effects were minimal and were limited to occasional mild thrombophlebitis.

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