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. 1998 Sep 1;95(18):10345-7.
doi: 10.1073/pnas.95.18.10345.

Nitric oxide in plant immunity

A Hausladen  1 , J S Stamler
Affiliations

Nitric oxide in plant immunity

A Hausladen et al. Proc Natl Acad Sci U S A. .
No abstract available

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Figures

Figure 1
Figure 1
The NO-signaling pathway. NOSs convert L-arginine to citrulline and a family of NO-related molecules. Exact N-oxide yields and identities vary as a function of experimental condition. The reaction requires cosubstrates/cofactors NADPH, O2, and tetrahydrobiopterin (BH4). Glutathione (GSH) may sustain enzyme activity and/or influence reaction product. Superoxide/hydrogen peroxide (O2−/H2O2) are typically generated by NOS, at least to some degree. NOSs may be regulated by Ca2+/calmodulin and other associated proteins. NO-elicited signals are mediated by cGMP, nitrosylation, or both. Although a growing list of signaling pathways are influenced by NO, sites of regulation by NO and NO-dependent interactions between signal transduction cascades are as yet poorly characterized. SNO, S-nitrosothiol; NOx, other oxides of nitrogen, in this case perhaps also including low mass metal-nitrosyl compounds.
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