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Review
. 1998 Aug;8(4):525-33.
doi: 10.1016/s0959-440x(98)80132-2.

Ion-channel-forming colicins

R M Stroud  1 , K Reiling, M Wiener, D Freymann
Affiliations
Review

Ion-channel-forming colicins

R M Stroud et al. Curr Opin Struct Biol. 1998 Aug.

Abstract

Several features of ion-channel-forming colicins have been illuminated by recent revelations: its four-domain structure, the mechanism and thermodynamics of binding to the gating loop of outer membrane porins, the mechanism of translocation, competition for the transperiplasmic excursion facilitated by the Tol or Ton transperiplasmic proteins, and the formation of a waisted, funnel-shaped transmembrane channel of well-characterized shape.

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