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. 1998;14(7):617-23.
doi: 10.1093/bioinformatics/14.7.617.

JOY: protein sequence-structure representation and analysis

K Mizuguchi  1 , C M Deane, T L Blundell, M S Johnson, J P Overington
Affiliations

JOY: protein sequence-structure representation and analysis

K Mizuguchi et al. Bioinformatics. 1998.

Abstract

Motivation: JOY is a program to annotate protein sequence alignments with three-dimensional (3D) structural features. It was developed to display 3D structural information in a sequence alignment and to help understand the conservation of amino acids in their specific local environments.

Results: : The JOY representation now constitutes an essential part of the two databases of protein structure alignments: HOMSTRAD (http://www-cryst.bioc.cam.ac.uk/homstrad ) and CAMPASS (http://www-cryst.bioc.cam.ac. uk/campass). It has also been successfully used for identifying distant evolutionary relationships.

Availability: The program can be obtained via anonymous ftp from torsa.bioc.cam.ac.uk from the directory /pub/joy/. The address for the JOY server is http://www-cryst.bioc.cam.ac.uk/cgi-bin/joy.cgi.

Contact: kenji@cryst.bioc.cam.ac.uk

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