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. 1998 Aug;179(2):481-5.
doi: 10.1016/s0002-9378(98)70383-7.

In pregnancies with gestational diabetes mellitus and intensive therapy, perinatal outcome is worse in small-for-gestational-age newborns

A García-Patterson  1 , R Corcoy, M Balsells, O Altirriba, J M Adelantado, L Cabero, A de Leiva
Affiliations

In pregnancies with gestational diabetes mellitus and intensive therapy, perinatal outcome is worse in small-for-gestational-age newborns

A García-Patterson et al. Am J Obstet Gynecol. 1998 Aug.

Abstract

Objective: This study analyzed the relationship between birth weight and perinatal outcome among women with gestational diabetes mellitus.

Study design: The relationship between perinatal outcome and birth weight was analyzed for 821 pregnancies of women with gestational diabetes mellitus attended in a tertiary hospital and receiving intensive metabolic therapy (normocaloric diet, self-monitoring of blood glucose level and individually tailored insulin regimen when needed). The Mantel-Haenszel test was used to adjust for preterm delivery.

Results: Seven percent of neonates were small for gestational age, 85% were appropriate for gestational age, and 8% were large for gestational age. After adjustment for preterm delivery the rates of adverse fetal outcome, low 1-minute Apgar score, and hypoglycemia were greater among small for gestational age neonates than among appropriate and large for gestational age infants (odds ratios 3.08, 2.51, and 3.17, respectively).

Conclusion: Among women with gestational diabetes mellitus who are receiving intensive therapy, perinatal outcome is worse for small for gestational age neonates than for appropriate and large for gestational age neonates.

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