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. 1998 Sep;42(9):2425-6.
doi: 10.1128/AAC.42.9.2425.

Prevalence and characterization of the mechanisms of macrolide, lincosamide, and streptogramin resistance in isolates of Streptococcus pneumoniae

N J Johnston  1 , J C De Azavedo, J D Kellner, D E Low
Affiliations

Prevalence and characterization of the mechanisms of macrolide, lincosamide, and streptogramin resistance in isolates of Streptococcus pneumoniae

N J Johnston et al. Antimicrob Agents Chemother. 1998 Sep.

Abstract

Of a total of 147 erythromycin-resistant Streptococcus pneumoniae isolates, 64 (43.5%) were resistant to erythromycin, clindamycin, and streptogramin B (MLSB phenotype), 57 of which possessed the ermB gene. Eighty-two (55.8%) were resistant to erythromycin alone (M phenotype), 81 of which possessed the mefE gene. One was erythromycin and streptogramin B resistant but susceptible to clindamycin (MS phenotype) and possessed neither the erm gene nor the mefE gene.

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Figures

FIG. 1
FIG. 1
Distribution of mefE and erm genes according to the MIC of erythromycin.
See this image and copyright information in PMC

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