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Comparative Study
. 1998 Sep;42(9):2459-62.
doi: 10.1128/AAC.42.9.2459.

Activities of gatifloxacin compared to those of seven other agents against anaerobic organisms

L M Ednie  1 , M R Jacobs, P C Appelbaum
Affiliations
Comparative Study

Activities of gatifloxacin compared to those of seven other agents against anaerobic organisms

L M Ednie et al. Antimicrob Agents Chemother. 1998 Sep.

Abstract

The agar dilution MIC was used to compare activities of gatifloxacin with those of ciprofloxacin, sparfloxacin, trovafloxacin, ampicillin, ampicillin-sulbactam, clindamycin, and metronidazole against 351 anaerobes. Overall MICs at which 50% of the isolates are inhibited and MICs at which 90% of the isolates are inhibited (in micrograms per milliliter) were as follows: gatifloxacin, 0.5 and 4; ciprofloxacin, 2 and 32; sparfloxacin, 2 and 8; trovafloxacin, 1 and 4; ampicillin, 1 and 64; ampicillin-sulbactam, 0.5 and 4; clindamycin, 0.125 and 8; and metronidazole, 1 and >16, respectively. Gatifloxacin MICs were similar to those of trovafloxacin in all organism groups.

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References

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