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Review
. 1998 Aug;2(4):519-28.
doi: 10.1016/s1367-5931(98)80129-4.

Antisense therapeutics

S Agrawal  1 , Q Zhao
Affiliations
Review

Antisense therapeutics

S Agrawal et al. Curr Opin Chem Biol. 1998 Aug.

Abstract

The field of antisense therapeutics has attracted great interest during the past decade. A large body of literature has recently appeared in which the antisense mechanism is claimed to be involved and a number of human clinical trials are underway. Questions regarding the specificity of action and side effects of antisense phosphorothioate oligonucleotides have arisen simultaneously.

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