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. 1976 Oct 16;2(6041):914-5.
doi: 10.1136/bmj.2.6041.914.

Muscle changes in acromegaly

M Nagulesparen, R Trickey, M J Davies, J S Jenkins

Muscle changes in acromegaly

M Nagulesparen et al. Br Med J. .

Abstract

Muscle biopsy specimens were obtained from 18 patients with acromegaly of varying degrees of severity. Half the specimens showed hypertrophy of type 1 fibres, while atrophy was most often seen in type 2 fibres. A direct correlation between muscle appearances and growth hormone levels was not observed. The needle biopsy technique is particularly suitable for determining the natural history of acrometalic myopathy.

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References

    1. Acta Neuropathol. 1973;24(4):273-86 - PubMed
    1. J Physiol. 1952 Feb;116(2):129-36 - PubMed

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