Peptide-bound hydroxylysine and large polypeptides related to collagen synthesis
- PMID: 976298
- DOI: 10.1111/j.1365-2362.1976.tb00529.x
Peptide-bound hydroxylysine and large polypeptides related to collagen synthesis
Abstract
About 10% of the urinary hydroxylysine is linked to peptides. There is no significant difference between the excretion of peptide-bound hydroxylysine and hydroxylysine measured in the non-dialysable fraction of the urine. Non-dialysable hydroxylysine is highly glycosylated and contains mainly glucosyl-galactosyl-hydroxylysine. It is concluded that the urinary peptide-bound hydroxylysine is present in the non-dialysable collagen polypeptides. Their unusual carbohydrate composition is discussed.
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