Gene targeting studies begin to reveal the function of neurofilament proteins
- PMID: 9763415
- PMCID: PMC2132816
- DOI: 10.1083/jcb.143.1.1
Gene targeting studies begin to reveal the function of neurofilament proteins
Erratum in
- J Cell Biol 1998 Nov 16;143(4):1142
Figures
Comment on
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Neurofilament-dependent radial growth of motor axons and axonal organization of neurofilaments does not require the neurofilament heavy subunit (NF-H) or its phosphorylation.J Cell Biol. 1998 Oct 5;143(1):171-81. doi: 10.1083/jcb.143.1.171. J Cell Biol. 1998. PMID: 9763429 Free PMC article.
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Disruption of the NF-H gene increases axonal microtubule content and velocity of neurofilament transport: relief of axonopathy resulting from the toxin beta,beta'-iminodipropionitrile.J Cell Biol. 1998 Oct 5;143(1):183-93. doi: 10.1083/jcb.143.1.183. J Cell Biol. 1998. PMID: 9763430 Free PMC article.
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Requirement of heavy neurofilament subunit in the development of axons with large calibers.J Cell Biol. 1998 Oct 5;143(1):195-205. doi: 10.1083/jcb.143.1.195. J Cell Biol. 1998. PMID: 9763431 Free PMC article.
References
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- Côté F, Collard JF, Julien JP. Progressive neuropathy in transgenic mice expressing the human neurofilament gene: a mouse model of amyotrophic lateral sclerosis. Cell. 1993;73:35–46. - PubMed
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- de Waegh SM, Lee VM-Y, Brady S. Local modulation of neurofilament phosphorylation, axonal caliber, and slow axonal transport by myelinating Schwann cells. Cell. 1992;68:451–468. - PubMed
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- Eyer J, Peterson A. Neurofilament-deficient axons and perikaryal aggregates in viable transgenic mice expressing a neurofilament β-galactosidase fusion protein. Neuron. 1994;12:389–405. - PubMed
