Genetic characterization of parainfluenza virus 3 derived from guinea pigs
- PMID: 9764404
- DOI: 10.1292/jvms.60.919
Genetic characterization of parainfluenza virus 3 derived from guinea pigs
Abstract
To understand the relationship between novel parainfluenza virus 3 (PIV-3), which has recently been isolated from the lungs of guinea pigs, and other PIV-3 strains, we determined the complete nucleotide sequence of the novel PIV-3 (GPv) genome. A comparison of the nucleotide sequence among PIV-3s, including bovine PIV-3, revealed that GPv is closely related to human PIV-3. The results of the phylogenetic analysis clearly showed that GPv is a lineage of human PIV-3, suggesting that GPv has probably been introduced into guinea pig colonies via infected humans.
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