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Review
. 1998 Oct;11(4):628-44.
doi: 10.1128/CMR.11.4.628.

Management of infections due to antibiotic-resistant Streptococcus pneumoniae

S L Kaplan  1 , E O Mason Jr
Affiliations
Review

Management of infections due to antibiotic-resistant Streptococcus pneumoniae

S L Kaplan et al. Clin Microbiol Rev. 1998 Oct.

Abstract

Antibiotic-resistant strains of Streptococcus pneumoniae are becoming more prevalent throughout the world; this has resulted in modifications of treatment approaches. Management of bacterial meningitis has the greatest consensus. Strategies for treating other systemic infections such as pneumonia, bacteremia, and musculoskeletal infections are evolving, in part related to the availability of new antibiotics which are active in vitro against isolates resistant to penicillin and the extended-spectrum cephalosporins. However, there are currently very limited data related to the clinical efficacy of these new agents. The studies upon which current recommendations are based are reviewed. Otitis media represents the single most common infection due to S. pneumoniae. Recommendations for treatment of acute otitis media due to drug-resistant strains and the rationale for these recommendations are discussed.

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References

    1. Abbasi S, Orlicek S L, Almohsen I, Luedtke G, English B K. Septic arthritis and osteomyelitis caused by penicillin and cephalosporin-resistant Streptococcus pneumoniae in a children’s hospital. Pediatr Infect Dis J. 1996;15:78–83. - PubMed
    1. Ahronheim G A, Reich B, Marks M I. Penicillin-insensitive pneumococci. Case report and review. Am J Dis Child. 1979;133:187–191. - PubMed
    1. Alonso J, Madrigal V, Garcia-Fuentes M. Recurrent meningitis from a multiply resistant Streptococcus pneumoniae strain treated with erythromycin. Pediatr Infect Dis J. 1991;10:256. . (Letter.) - PubMed
    1. Alper C M, Doyle W J, Seroky J T, Bluestone C D. Efficacy of clarithromycin treatment of acute otitis media caused by infection with penicillin-susceptible, -intermediate, and -resistant Streptococcus pneumoniae in the chinchilla. Antimicrob Agents Chemother. 1996;40:1889–1892. - PMC - PubMed
    1. American Academy of Pediatrics. Dexamethasone therapy for bacterial meningitis. In: Peter G, editor. Red book: Report of the Committee on Infectious Diseases. 24th ed. Elk Grove Village, Ill: American Academy of Pediatrics; 1997. pp. 620–622.

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