Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
. 1998 Jul;79(1):63-4.
doi: 10.1136/adc.79.1.63.

Melatonin treatment in an institutionalised child with psychomotor retardation and an irregular sleep-wake pattern

G Pillar  1 , A Etzioni, E Shahar, P Lavie
Affiliations
Case Reports

Melatonin treatment in an institutionalised child with psychomotor retardation and an irregular sleep-wake pattern

G Pillar et al. Arch Dis Child. 1998 Jul.

Abstract

An institutionalised 13 year old girl with psychomotor retardation suffered from an irregular sleep-wake pattern. Multiple measurements of urinary sulphatoxy-melatonin (aMT6) concentrations were abnormally low, without any significant day-night differences. Administration of exogenous melatonin (3 mg) at 18:00 resulted in increased nocturnal urinary aMT6 concentrations and improvements in her sleep-wake pattern. Melatonin may help disabled children suffering from sleep disorders.

PubMed Disclaimer

Similar articles

See all similar articles

Cited by

References

    1. J Neural Transm Suppl. 1986;21:375-94 - PubMed
    1. Clin Chem. 1987 Aug;33(8):1343-8 - PubMed
    1. Lancet. 1988 Apr 2;1(8588):772-3 - PubMed
    1. Pediatrics. 1991 Apr;87(4):494-9 - PubMed
    1. J Ment Defic Res. 1991 Aug;35 ( Pt 4):269-90 - PubMed

Publication types