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Case Reports
. 1998 Jul;79(1):63-4.
doi: 10.1136/adc.79.1.63.

Melatonin treatment in an institutionalised child with psychomotor retardation and an irregular sleep-wake pattern

G Pillar  1 , A Etzioni, E Shahar, P Lavie
Affiliations
Case Reports

Melatonin treatment in an institutionalised child with psychomotor retardation and an irregular sleep-wake pattern

G Pillar et al. Arch Dis Child. 1998 Jul.

Abstract

An institutionalised 13 year old girl with psychomotor retardation suffered from an irregular sleep-wake pattern. Multiple measurements of urinary sulphatoxy-melatonin (aMT6) concentrations were abnormally low, without any significant day-night differences. Administration of exogenous melatonin (3 mg) at 18:00 resulted in increased nocturnal urinary aMT6 concentrations and improvements in her sleep-wake pattern. Melatonin may help disabled children suffering from sleep disorders.

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