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Comparative Study
. 1998 Nov;36(11):3382-4.
doi: 10.1128/JCM.36.11.3382-3384.1998.

Evaluation of a commercial PCR kit for diagnosis of cytomegalovirus infection of the central nervous system

A Weinberg  1 , D Spiers, G Y Cai, C M Long, R Sun, V Tevere
Affiliations
Comparative Study

Evaluation of a commercial PCR kit for diagnosis of cytomegalovirus infection of the central nervous system

A Weinberg et al. J Clin Microbiol. 1998 Nov.

Abstract

We evaluated the AMPLICOR cytomegalovirus (CMV) PCR kit for the diagnosis of neurologic CMV infections on 43 positive and 112 negative archived cerebrospinal fluid specimens originally tested by an in-house PCR method. The AMPLICOR kit showed sensitivity and specificity of 95 and 100%, respectively, versus the home-grown assay, indicating its utility in this clinical setting.

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References

    1. Achim C L, Nagra R M, Wang R, Nelson J A, Wiley C A. Detection of cytomegalovirus in cerebrospinal fluid autopsy specimens from AIDS patients. J Infect Dis. 1994;169:623–627. - PubMed
    1. Arribas R J, Clifford D C, Fichtenbaum J C, Commins L D, Powderly G W, Stroch A G. Level of cytomegalovirus (CMV) DNA in cerebrospinal fluid of subjects with AIDS and CMV infection of the central nervous system. J Infect Dis. 1995;172:527–531. - PubMed
    1. Arribas R J, Stroch A G, Clifford B D, Tselis C A. Cytomegalovirus encephalitis. Ann Intern Med. 1996;125:577–587. - PubMed
    1. Cinque P, Vago L, Brytting M, Castagna A, Accordini A, Sundqvist A V, Zanchetta N, Monoforte D A, Wahren B, Larrarin A, Linde A. Cytomegalovirus infection of the central nervous system in patients with AIDS: diagnosis by DNA amplification from cerebrospinal fluid. J Infect Dis. 1992;166:1408–1411. - PubMed
    1. Conway J H, Weinberg A, Ashley R L, Amer J, Levin M J. Viral meningitis in a preadolescent child caused by reactivation of latent herpes simplex (type 1) J Pediatr Infect Dis. 1997;16:627–629. - PubMed

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