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Review
. 1998 Sep;28(5):1057-62.
doi: 10.1016/s0195-5616(98)50102-7.

The effects of dental disease on systemic disease

Affiliations
Review

The effects of dental disease on systemic disease

L J DeBowes. Vet Clin North Am Small Anim Pract. 1998 Sep.

Abstract

Chronic exposure to periodontal pathogens results in the continued stimulation of an immune and nonimmune response by the host. The cytokines and other inflammatory mediators produced in gingivitis/periodontitis result in local tissue destruction and may reach significant levels affecting the cardiovascular system or placental tissues. The oral cavity may also serve as a direct reservoir for bacterial contamination of the lungs with subsequent development of bacterial pneumonia.

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