Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Clinical Trial
. 1998 Oct;51(4):1221-3.
doi: 10.1212/wnl.51.4.1221.

Encouraging initial response of restless legs syndrome to pramipexole

P M Becker  1 , W Ondo, D Sharon
Affiliations
Clinical Trial

Encouraging initial response of restless legs syndrome to pramipexole

P M Becker et al. Neurology. 1998 Oct.

Abstract

Restless legs syndrome (RLS) is a common condition that results in uncomfortable sensations and an urge to move the limbs. Two centers tested a new dopamine agonist, pramipexole, in 23 patients with RLS in a time-limited, open-label, clinical trial. After 4 weeks or more, 19 patients reported significant improvement as assessed by the short International Restless Legs Syndrome Study Group questionnaire (p < 0.0001). These encouraging preliminary results justify larger, controlled trials for pramipexole in patients with RLS.

PubMed Disclaimer

Comment in

  • Restless legs syndrome.
    Gálvez-Jiménez N, Khan T, Hanson M. Gálvez-Jiménez N, et al. Neurology. 1999 Jul 22;53(2):439-40. doi: 10.1212/wnl.53.2.437-d. Neurology. 1999. PMID: 10430455 No abstract available.

Publication types

LinkOut - more resources