A nucleolus-associated coiled body

Abstract

One or two healthy structures frequently have been observed attached to nucleoli in facial motor neurons of the golden hamster. These round-to-oval structures, called "coiled bodies", were seen at 15, 19, and 24 days postnatal and in the adult, both in normal neurons and in chromatolytic neurons which had been axotomized 4 days previously. With one exception, the coiled bodies were seen to be attached via fibrillar material to the nucleolar periphery. Although the numbers of coiled bodies may be altered during neuronal maturation and as a result of axon section, the bodies revealed no structural alterations that could be attributed to developmental age or to experimental trauma.