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Case Reports
. 1998 Sep;11(2):147-50.
doi: 10.1111/j.1468-3083.1998.tb00768.x.

Bullous erythema multiforme following herpes zoster and varicella-zoster virus infection

K Weisman  1 , C S Petersen, C W Blichmann, N H Nielsen, B M Hultberg
Affiliations
Case Reports

Bullous erythema multiforme following herpes zoster and varicella-zoster virus infection

K Weisman et al. J Eur Acad Dermatol Venereol. 1998 Sep.

Abstract

Four cases of herpes zoster-induced bullous erythema multiforme (EM) are reported. Three patients presented with widespread skin lesions 10 to 14 days after an episode of thoracic herpes zoster. In these patients a high increase in varicella-zoster virus (VZV) antibody titer was detected, indicating secondary VZV infection. Histologic examinations of skin biopsy from a patient with widespread lesions (case 4) revealed a mixture of EM, toxic epidermal necrolysis and herpetic virus infection. VZV should be included in the list of infectious agents able to trigger EM and Stevens-Johnson syndrome.

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