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Clinical Trial
. 1998 Sep;40(3):223-5.

Time length of negativization of hCG serum values after either surgical or medical treatment of ectopic pregnancy

N Colacurci  1 , P De Franciscis, R Zarcone, N Fortunato, M Passaro, A Mollo, G Russo
Affiliations
  • PMID: 9785922
Clinical Trial

Time length of negativization of hCG serum values after either surgical or medical treatment of ectopic pregnancy

N Colacurci et al. Panminerva Med. 1998 Sep.

Abstract

Objective: The aim of this study was to compare the time length until the human chorionic gonadotropin titer became negative after medical or surgical treatment of ectopic pregnancy.

Experimental design: Prospective, randomized study. PARTECIPANTS AND INTERVENTIONS: We compared time to resolution in 30 cases of tubal pregnancies successfully treated, 15 underwent laparoscopic linear salpingostomy (group 1) and 15 medical treatment with single-ose methotrexate (group 2). The patients of both groups had no meaningful differences of age, gestational age and human chorionic gonadotropin mean values.

Measures: During the follow-up human chorionic gonadotropin serum values were obtained every two days until the titer was negative.

Results: The time to resolution was 33.6 +/- 6.6 days in group 1, 31.5 +/- 7.8 in group 2 with no statistically meaningful differences.

Conclusion: The data, comparable with results obtained by laparoscopic treatment, suggest that human chorionic gonadotropin value becomes negative independently of type of treatment and residual trophoblast.

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