Two giant basal cell carcinomas presenting simultaneously in the same patient, one resulting in lower extremity limb loss

Abstract

Giant basal cell carcinomas are a rare form of the most common malignant neoplasm of the skin. They are commonly found on the trunk and display a more aggressive behavior, resulting in local invasion and metastasis. Giant basal cell carcinomas that reach a critical size of 10 cm in diameter almost always present with metastases. We present an 82-year-old woman who presented with two giant basal cell carcinomas of critical size-one that occurred on the lower extremity and resulted in limb loss without any sign of metastasis.