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Case Reports
. 1998 Oct;21(10):777-9.
doi: 10.1002/clc.4960211017.

Doxorubicin-induced cardiomyopathy treated with carvedilol

S Fazio  1 , E A Palmieri, B Ferravante, F Bonè, B Biondi, L Saccà
Affiliations
Case Reports

Doxorubicin-induced cardiomyopathy treated with carvedilol

S Fazio et al. Clin Cardiol. 1998 Oct.

Abstract

Even today, heart failure due to doxorubicin-induced dilated cardiomyopathy seems to have a poor prognosis, as it is often irreversible and relatively unresponsive to standard medical treatment. This paper describes the first case of a patient complaining of severe symptoms of congestive heart failure due to doxorubicin-induced dilated cardiomyopathy unresponsive to standard medical treatment (digoxin, diuretics, and angiotensin-converting enzyme inhibitor), who showed complete clinical recovery and significant improvement of left ventricular dysfunction after carvedilol treatment. It also illustrates the possibility that carvedilol may be a first-choice drug for the treatment of this disease.

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References

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