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Review
. 1998 Sep;4(9):404-11.
doi: 10.1016/s1357-4310(98)01329-x.

Testicular germ cell tumors: molecular understanding and clinical implications

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Review

Testicular germ cell tumors: molecular understanding and clinical implications

S G Lutzker et al. Mol Med Today. 1998 Sep.

Abstract

It was recognized in the 1960s that testicular germ cell tumors were curable with chemotherapeutic drugs. Since that time, newer drugs including cisplatin have increased the cure rate of these tumors to over 80%, even in patients with metastatic disease. Germ cell tumors also exhibit a unique biology and genetics that distinguish them from other solid tumors and might contribute to their routine curability.

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