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Clinical Trial
. 1998 Jul;21(1):1-6.
doi: 10.1016/s0169-5002(98)00046-4.

Long-term follow-up of patients enrolled in a randomized trial comparing perioperative chemotherapy and surgery with surgery alone in resectable stage IIIA non-small-cell lung cancer

J A Roth  1 , E N Atkinson, F Fossella, R Komaki, M Bernadette Ryan, J B Putnam Jr, J S Lee, H Dhingra, L De Caro, M Chasen, W K Hong
Affiliations
Clinical Trial

Long-term follow-up of patients enrolled in a randomized trial comparing perioperative chemotherapy and surgery with surgery alone in resectable stage IIIA non-small-cell lung cancer

J A Roth et al. Lung Cancer. 1998 Jul.

Abstract

Our previously reported randomized study of patients with untreated, potentially resectable clinical stage IIIA non-small-cell lung cancer found that patients treated with perioperative chemotherapy and surgery had a significant increase in median survival compared to patients treated with surgery alone. We have now re-analyzed the results of the study with a median time from random allocation to analysis for all patients of 82 months. The increase in survival conferred by perioperative chemotherapy was maintained during the period of extended observation.

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