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. 1998 Sep;331(9):273-8.
doi: 10.1002/(sici)1521-4184(19989)331:9<273::aid-ardp273>3.0.co;2-r.

Research on heterocyclic compounds, Part 40. 2-Phenylimidazo[1,2-a]pyridine-3-carboxylic acid derivatives: synthesis and antiinflammatory activity

A Di Chiacchio  1 , M G Rimoli, L Avallone, F Arena, E Abignente, W Filippelli, A Filippelli, G Falcone
Affiliations

Research on heterocyclic compounds, Part 40. 2-Phenylimidazo[1,2-a]pyridine-3-carboxylic acid derivatives: synthesis and antiinflammatory activity

A Di Chiacchio et al. Arch Pharm (Weinheim). 1998 Sep.

Abstract

A series of 2-phenylimidazo[1,2-a]pyridine-3-carboxylic esters, acids, and amides were synthesized and pharmacologically tested in order to evaluate their antiinflammatory and analgesic activity and their ulcerogenic action on the gastro-intestinal tract. The most active member of this series of compounds was found to be 6-methyl-2-phenylimidazo[1,2-a]pyridine-3-carboxylic acid (5c).

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