Review
doi: 10.1016/s0959-437x(98)80007-5.
Genetic dissection of glucocorticoid receptor function in mice
Affiliations
- PMID: 9794823
- DOI: 10.1016/s0959-437x(98)80007-5
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Review
Genetic dissection of glucocorticoid receptor function in mice
Curr Opin Genet Dev.
1998 Oct.
Abstract
Upon hormone binding, the activated glucocorticoid receptor (GR) functions as a transcription factor via different modes of action to control gene expression. Recent gene-targeting studies in mice provide new insight into the role of GR in vivo and are helping decipher the molecular mechanisms underlying its actions.
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