Trials: the next 50 years. Large scale randomised evidence of moderate benefits
- PMID: 9794846
- PMCID: PMC1114150
- DOI: 10.1136/bmj.317.7167.1170
Trials: the next 50 years. Large scale randomised evidence of moderate benefits
Comment in
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Patients who are eligible but not randomised should be included as additional comparative arm in study.BMJ. 1999 Mar 27;318(7187):874-5. doi: 10.1136/bmj.318.7187.874a. BMJ. 1999. PMID: 10092280 Free PMC article. No abstract available.
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Clinical trials. Simple megatrials are not sufficient.BMJ. 1999 Apr 24;318(7191):1138. doi: 10.1136/bmj.318.7191.1138. BMJ. 1999. PMID: 10213738 Free PMC article. No abstract available.
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Clinical Trials. Randomised database studies could serve as new strategy.BMJ. 1999 Apr 24;318(7191):1138. BMJ. 1999. PMID: 10366263 No abstract available.
References
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- Collins R, Peto R, Gray R, Parish S. Large-scale randomised evidence: trials and overviews. In: Maynard A, Chalmers I, editors. Non-random reflections on health services research. London: BMJ Books; 1998. pp. 197–230.
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- The Cochrane Library. Cochrane Collaboration; Issue 3. Oxford: Update Software; 1998.
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- CAST (Chinese Acute Stroke Trial) Collaborative Group. CAST: randomised placebo-controlled trial of early aspirin use in 20,000 patients with acute ischaemic stroke. Lancet. 1997;349:1641–1649. - PubMed
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- ISIS-2 (Second International Study of Infarct Survival) Collaborative Group. Randomised trial of intravenous streptokinase, oral aspirin, both, or neither among 17,187 cases of suspected acute myocardial infarction. Lancet. 1988;ii:349–360. - PubMed
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