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. 1976 Jul 31;2(5):168-70.

Spironolactone and acute mountain sickness

T T Currie, P H Carter, W L Champion, G Fong, J K Francis, I H McDonald, R K Newing, I N Nunn, R N Sisson, M Sussex, R F Zacharin
  • PMID: 979834

Spironolactone and acute mountain sickness

T T Currie et al. Med J Aust. .

Abstract

Thirteen adults trekking in Nepal in 1974 to altitudes between 4,300 m and 5,500 m remained free from acute mountain sickness while taking spironolactone as a prophylactic measure. Two years previously five of these adults trekking at similar altitudes, but without treatment, had suffered from acute mountain sickness. The regime used was spironolactone in a dosage of 25 mg three times a day for two days preceding and during the periods spent at altitudes above 3,000 m.

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