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. 1998 Jul-Aug;50(7-8):329-31.

[Menopause. Hormone substitution therapy and prevention of cardiovascular risk]

[Article in Italian]
R Grio  1 , A Cellura, M Porpiglia, R Geranio, R Piacentino
Affiliations
  • PMID: 9808958

[Menopause. Hormone substitution therapy and prevention of cardiovascular risk]

[Article in Italian]
R Grio et al. Minerva Ginecol. 1998 Jul-Aug.

Abstract

Background and aims: Cardiovascular disease is the major cause of death in over 60-year-old women. The mean age of onset is about 10 years later in women compared to men, a difference which can be explained by the end of physiological estrogen production in menopause.

Methods: The authors treated a group of 68 menopausal patients with HRT for a period of 5 years.

Results: A series of positive effects emerged from the study which were potentially capable of preventing ischemic cardiopathy.

Conclusions: The authors reached the conclusion that--owing to its beneficial effects on lipid and glucose metabolism, as well as on coagulation factors and arterial pressure--HRT is able to prevent cardiovascular disease, reducing the risk of infarction by between 20 and 50%.

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