Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Comparative Study
. 1998 Nov 23;812(1-2):113-20.
doi: 10.1016/s0006-8993(98)00960-3.

Escapable and inescapable stress differentially alter extracellular levels of 5-HT in the basolateral amygdala of the rat

J Amat  1 , P Matus-Amat, L R Watkins, S F Maier
Affiliations
Comparative Study

Escapable and inescapable stress differentially alter extracellular levels of 5-HT in the basolateral amygdala of the rat

J Amat et al. Brain Res. .

Abstract

The effects of escapable and yoked inescapable electric tailshocks on extracellular levels of serotonin (5-HT) in the basolateral amygdala were measured by in vivo microdialysis. Inescapable, but not escapable, shock increased extracellular 5-HT in the amygdala relative to restrained controls. Basal levels of 5-HT were elevated 24 h after inescapable shock, and previously inescapably shocked subjects exhibited an exaggerated 5-HT response to two brief footshocks. Levels of extracellular 5-HIAA did not follow any particular pattern and were not correlated with the changes in 5-HT.

PubMed Disclaimer

Publication types

LinkOut - more resources