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. 1998 Nov-Dec;48(6):333-7.
doi: 10.1159/000022825.

Limb girdle muscular dystrophy type 2A (CAPN3): mapping using allelic association

C Lonjou  1 , A Collins, J Beckmann, V Allamand, N Morton
Affiliations

Limb girdle muscular dystrophy type 2A (CAPN3): mapping using allelic association

C Lonjou et al. Hum Hered. 1998 Nov-Dec.

Abstract

Recently a graphical study of linkage disequilibrium around the CAPN3 locus failed to refine the 1.3-Mb interval suggested by haplotype sharing. On the contrary, the Malecot model as implemented in the ALLASS program maps CAPN3 within 3 kb of its true location (23 kb from the locus midpoint), overcoming identified problems with small samples, interrelated sibships, and short duration.

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