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Review
. 1998 Oct;28(5):439-45.
doi: 10.1023/a:1026008606672.

Finding specific genes that cause autism: a combination of approaches will be needed to maximize power

S E Folstein  1 , E Bisson, S L Santangelo, J Piven
Affiliations
Review

Finding specific genes that cause autism: a combination of approaches will be needed to maximize power

S E Folstein et al. J Autism Dev Disord. 1998 Oct.

Abstract

Although autism is clearly inherited, it may be challenging to find the genes involved: The mechanism of inheritance is unknown, families with an autistic child are usually small, parent-child pairs are rare, and a fairly large number of genes may be involved, some or all of which may have a small effect on the phenotype. We discuss several strategies for finding genes, all of which may be used in combination to find the relevant genes.

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