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. 1976 Oct 22;194(4263):428-31.
doi: 10.1126/science.982025.

Activation of histone gene transcription by nonhistone chromosomal phosphoproteins

J A Thompson, J L Stein, L J Kleinsmith, G S Stein

Activation of histone gene transcription by nonhistone chromosomal phosphoproteins

J A Thompson et al. Science. .

Abstract

Hybridization analysis of RNA transcripts from HeLa S3 cell chromatin to histone complementary DNA indicates that a chromosomal phosphoprotein fraction activates transcription of histone messenger RNA sequences in vitro with chromatin from a phase in the cell cycle when histone genes are normally silent.

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