Outcome of IVF in patients with endometriosis in comparison with tubal-factor infertility
- PMID: 9822979
- PMCID: PMC3454921
- DOI: 10.1023/a:1022526002421
Outcome of IVF in patients with endometriosis in comparison with tubal-factor infertility
Abstract
Purpose: The aim of this retrospective study was to compare the outcome of in vitro fertilization and embryo transfer in women with endometriosis and a control group with tubal-factor infertility.
Methods: Forty-eight patients with endometriosis underwent 65 cycles of in vitro fertilization and embryo transfer at Huddinge University Hospital. The matched control group with tubal-factor infertility consisted of 98 cycles in 98 patients. These groups were retrospectively analyzed regarding stimulation, fertilization, embryo development, implantation, and pregnancy outcome.
Results: The fertilization rate was significantly lower in women with endometriosis, but the cleavage, implantation, and pregnancy rates did not differ.
Conclusions: Our results show that women with endometriosis have a lower fertilization rate compared with women with tubal-factor infertility. However, once the oocyte is fertilized, it seems that the preembryo has a normal chance of implantation, leading to similar pregnancy rates.
Comment in
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Does endometriosis have an adverse effect on the fertilization in vitro and the IVF outcome?J Assist Reprod Genet. 1998 Oct;15(9):527-9. doi: 10.1023/a:1022591518351. J Assist Reprod Genet. 1998. PMID: 9822978 Free PMC article. No abstract available.
References
-
- Arici A, Oral E, Bukulmez O, Duleba A, Olive DL, Jones EE. The effect of endometriosis on implantation: results from the Yale University in vitro fertilization and embryo transfer program. Fertil Steril. 1996;65:603–607. - PubMed
-
- Hill JA. Immunologic factors in endometriosis and endometriosis-associated reproductive failure. Infert Reprod Med Clin North Am. 1992;3:583–596.
-
- Gleicher N. Endometriosis, a new approach is needed. Hum Reprod. 1992;7:821–824. - PubMed
-
- Shushan A, Eisenberg VH, Schenker JG. Subfertility in the era of assisted reproduction: Changes and consequences. Fertil Steril. 1995;64:459–469. - PubMed
-
- Mahmood TA, Arumugam K, Templeton AA. Oocyte and follicular fluid characteristics in women with mild endometriosis. Br J Obstet Gynecol. 1991;8:573–577. - PubMed
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