[Effect of ultraviolet irradiation of different spectral composition on cholesterol synthesis in rat skin]
- PMID: 982620
[Effect of ultraviolet irradiation of different spectral composition on cholesterol synthesis in rat skin]
Abstract
Irradiation of rats with of UV-radiation sources epsilonYB-15, (see article) causes a decrease in the intensity of 2-14C-acetate incorporation into cholesterol of skin and small intestine and simultaneous accumulation of radioactivity in its predecessors, namely in lathosterol and 7-dehydrocholesterol. Thus, it is shown that UV-irradiation of animals inhibits the cholesterol synthesis in skin and tissue of the small intestine. Intensity of cholesterol synthesis inhibition with UV-irradiation of animals depends on the spectral, composition of the acting radiation.