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Review
. 1998;48(1):19-28.
doi: 10.1002/(SICI)1097-0282(1998)48:1<19::AID-BIP3>3.0.CO;2-I.

Reading DNA differently

Y Gat  1 , D G Lynn
Affiliations
Review

Reading DNA differently

Y Gat et al. Biopolymers. 1998.

Abstract

Product inhibition has provided the limiting barrier to efficient template-directed ligation and polymerization reactions. Here we review the attempts to circumvent this limitation and outline a translation strategy that does overcome the barrier and allows the information encoded in DNA to be read and amplified into backbone-modified oligonucleotides.

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