Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1976 Sep;32(3):324-6.
doi: 10.1128/aem.32.3.324-326.1976.

Inhibition of aflatoxin formation by 2-mercaptoethanol

S K Gupta, K K Maggon, T A Venkitasubramanian

Inhibition of aflatoxin formation by 2-mercaptoethanol

S K Gupta et al. Appl Environ Microbiol. 1976 Sep.

Abstract

2-Mercaptoethanol inhibits growth of Aspergillus parasiticus NRRL 3240 and aflatoxin formation by the fungus. When added to the resuspended medium, 2-mercaptoethanol inhibited [1-14C]acetate incorporation into both aflatoxins and neutral lipids, thereby showing that it acts at an early stage of aflatoxin biosynthesis. The inhibition is probably due to its chelating action on zinc, which is essential for aflatoxin production. It is proposed that any chelating agent that selectively binds to zinc will inhibit aflatoxin formation.

PubMed Disclaimer

Similar articles

See all similar articles

Cited by

  • Biosynthesis of aflatoxins.
    Maggon KK, Gupta SK, Venkitasubramanian TA. Maggon KK, et al. Bacteriol Rev. 1977 Dec;41(4):822-55. doi: 10.1128/br.41.4.822-855.1977. Bacteriol Rev. 1977. PMID: 23090 Free PMC article. Review. No abstract available.
  • Inhibition of aflatoxin biosynthesis by tolnaftate.
    Khan SN, Maggon KK, Venkitasubramanian TA. Khan SN, et al. Appl Environ Microbiol. 1978 Aug;36(2):270-3. doi: 10.1128/aem.36.2.270-273.1978. Appl Environ Microbiol. 1978. PMID: 697362 Free PMC article.

References

    1. Appl Microbiol. 1965 Mar;13:208-11 - PubMed
    1. J Biol Chem. 1966 Oct 10;241(19):4406-10 - PubMed
    1. Biochim Biophys Acta. 1968 Jul 9;159(3):490-5 - PubMed
    1. Anal Biochem. 1970 Dec;38(2):568-71 - PubMed
    1. Appl Microbiol. 1974 Nov;28(5):763-7 - PubMed

MeSH terms

LinkOut - more resources