Review
[Role of inositol triphosphate in the formation of the calcium signal in T-lymphocytes]
[Article in
Russian]
Affiliations
- PMID: 9848195
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Review
[Role of inositol triphosphate in the formation of the calcium signal in T-lymphocytes]
[Article in
Russian]
Ukr Biokhim Zh (1978).
1998 Jul-Aug.
Abstract
The mechanisms of TCR/CD3 complex and phospholipase C interaction, inositol-1,4,5-triphosphate role in both initial transient and sustained elevation of intracellular Ca2+ and in calcium oscillations driving following T cells stimulation are discussed. Data on IP3-receptors structure and localisation in lymphocytes are summarized.
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