Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1976 Aug 15;158(2):473-6.
doi: 10.1042/bj1580473.

Liposomal retention of a modified anti-inflammatory steroid

I H Shaw, C G Knight, J T Dingle

Liposomal retention of a modified anti-inflammatory steroid

I H Shaw et al. Biochem J. .

Abstract

In studies with synthetic lecithins, dipalmitoylphosphatidylcholine was found to be the preferred form for liposomal retention of cortisol esters at 37 degrees C. Cortisol palmitate was retained longer than cortisol octanoate, whereas unesterified cortisol escaped readily from liposomes. Such a liposome composition may allow the controlled release of modified anti-inflammatory agents, particularly when used for intra-articular administration.

PubMed Disclaimer

References

    1. Biochemistry. 1973 Jun 5;12(12):2351-60 - PubMed
    1. Clin Sci Mol Med. 1975 Aug;49(2):99-106 - PubMed
    1. Biophys J. 1975 Nov;15(11):1117-24 - PubMed
    1. Ann Rheum Dis. 1974 Jan;33(1):62-6 - PubMed
    1. J Lab Clin Med. 1974 Apr;83(4):640-7 - PubMed

MeSH terms