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. 1976 Aug 15;158(2):477-9.
doi: 10.1042/bj1580477.

Localization of thyroid peroxidase and the site of iodination in rat thyroid gland

H H Edwards, M Morrison

Localization of thyroid peroxidase and the site of iodination in rat thyroid gland

H H Edwards et al. Biochem J. .

Abstract

The iodinated protein was localized in thyroid tissue slices by using radioautography. In unfixed tissue, the labelled protein was localized in the colloid, whereas, in tissue that was fixed before the 125I addition, the label was within the follicular cell. This localizes thyroid peroxidase largely on the endoplasmic reticulum of the cell.

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