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. 1998;25(3):83-5.

Artificial endometrial preparation for oocyte donation using synthetic estrogen and progestogen

A Abu-Musa  1 , A Hannoun, A Khalil, Z Masaad, K Karam
Affiliations
  • PMID: 9856304

Artificial endometrial preparation for oocyte donation using synthetic estrogen and progestogen

A Abu-Musa et al. Clin Exp Obstet Gynecol. 1998.

Abstract

Objective: To evaluate the outcome of an oocyte donation program using synthetic estrogen and progestational agents for uterine preparation.

Methods: Conjugated estrogen, 1.25 mg per day at increasing doses and dydrogesterone, a synthetic progestogen, 30 mg per day were used for uterine priming. All embryo transfers were done on day 2 of progestogen supplementation.

Results: The pregnancy rates were 38% per embryo transfer. The ongoing pregnancy rate was 31% with an abortion rate of 20%.

Conclusion: Endometrial preparation in an oocyte donation program using orally administered synthetic estrogen and progestogen gives pregnancy rates comparable to those reported with natural products.

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