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. 1976 Sep 3;193(4256):899-900.
doi: 10.1126/science.986086.

Diamond-Blackfan syndrome: lymphocyte-mediated suppression of erythropoiesis

R Hoffman, E D Zanjani, J Vila, R Zalusky, J D Lutton, L R Wasserman

Diamond-Blackfan syndrome: lymphocyte-mediated suppression of erythropoiesis

R Hoffman et al. Science. .

Abstract

Peripheral blood lymphocytes from six patients with congenital hypoplastic anemia suppressed erythroid cell formation by normal human bone marrow cells in response to erythropoietin in vitro. The results suggest that the anemia in these children has an immunologic basis.

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